Alumni | mysite

Listed below are former Legleiter lab members , including those from WVU and a variety of summer research programs.

Graduate Student Alumni

Kathleen Burke, PhD

The interaction of huntingtin with lipid bilayers is modulated by polyglutamine length and flanking sequences

Jim Arndt, PhD

Ion mobility-mass spectrometry for structural characterization and applied ‘omics: a study in neurodegenerative diseases,
co-advised with Dr. Stephen Valentine

Maryssa Beasley, PhD

The effects of membrane physicochemical properties on huntingtin membrane association and downstream aggregation

Adewale Adegbuyiro, PhD

Huntingtin aggregation at interfaces associated with membranes and organelles

Chathuranga Siriwardhana, PhD

Lipid binding properties of huntingtin as a novel therapeutic target

Elizabeth Yates, PhD

Surfaces modulate ß-amyloid peptide aggregation associated with Alzheimer’s disease

Maxmore Chaibva, PhD

Factors Modulating the Interaction of Huntingtin with Lipid Membranes: Implications for Huntington's Disease

Faezeh Sedighi, PhD

Targeting the Nt17 of the huntingtin protein via natural and chemical modifications: impact on aggregation and membrane interactions

Alyssa Stonebraker, PhD

Investigation of Early Complex Formation of Huntingtin Protein With and Without Lipids

Xiang Gao, MS

Cholesterol Modulates Huntingtin Binding to and Aggregation on Lipid Membranes

Nicole Shamitko-Klingensmith, PhD

Investigating the role of mechanical properties in biological systems

Albert Pilkington, PhD

The impact of post translational modification on the aggregation of the ß-amyloid peptide in the presence or absence of lipids

Sharon Groover, PhD

Factors Influencing Huntingtin Aggregation at Surfaces: Implications for Huntington’s Disease

Adam Skeens, PhD

Exogenous factors that impact huntingtin aggregation

Bharath Kumar

AFM physics and spirochete mechanics

Gabriella Pettipas, MS

S(+)-Propylnorapomorphine Hydrochloride Alters Mutant Huntingtin Aggregation and Membrane Interactions

Undergraduate Alumni

Anthony Giovengo

SPAM project and characterization of purified organelles

Kaitlin Hansel

Huntingtin purification and lipid interactions

George Magnone

AFM simulations and bilayer properties

Sherry Finkel

Amyloid fragment lipid interactions / teaching modules

Pranav Jain

Role of lipid composition in htt aggregation and aggregation of the androgen receptor

Katie Kapp

Peptide inhibition of htt aggregation

Alyssa Stonebraker

Screening compounds to interfere with htt/lipid binding

Caleb Fan

Impact of molecular crowding on amyloid formation

Rachel Hankin

Peptide aggregation inhibitors

Zulkl Jaffary

Htt aggregation

Sophia “Eiley” Massinople

Peptide seeds of htt aggregation

Emily Wyda

Htt aggregation

Tyler Girman

Impact of small molecule amyloid inhibiters on C. elegans expressing htt

Jordan Godbey

htt purification, aggregation, and morphology

Elana Cucco

Aggregation of amyloid fragments

Sam Umbaugh

Huntington interaction with lipids and PDA assay development

Connor Levy

Seeding effects of huntingtin fragments

Ashley Leslie

Huntingtin and Aß aggregation in the presence of lipids

Barry Liang

Small molecule aggregation inhibitors

Garima Agarwal

Development of lipid/protein aggregation assays

Katelyn Taylor

Impact of molecular crowding on amyloid formation

Allison Gorman

Oxidation of amyloid fibrils

Breanna Hodges

Impact of molecular crowding on amyloid formation

Michelle Wunder

Peptide seeds of htt aggregation

Zachary Ellis

Mechanical properties of C. elegans expressing htt

Korina Pebley

Impact of small molecule amyloid inhibiters on C. elegans expressing htt

Phillip Pifer

SPAM project and the interaction of mutant peptides with lipid bilayers

Michael Lynch

Aggregation of amyloid fragments

Kelley Molchanoff (Wambaugh)

AFM physics and membrane properties

Olivia Sarver

Acetylation of huntingtin

Peter Grimson

Lipid phase separation

Morgan Nyman

Impact of acetylation on ß-amyloid peptide

John Bard

Impact of pre-aggregation on htt/lipid binding

Timothy Ferrebee

Impact of oxidation on ß-amyloid peptide

Iraj Hassan

Small molecule modifiers of amyloid formation

Emily Donley

Small peptide inhibitors of htt aggregation

Laiken Cook

Htt aggregation in C. elegans

Kaitlyn Keith

Manipulating htt aggregation in C. elegans

Victoria Ayers

Htt aggregation in C. elegans

Josie Baird

Drug screening